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Cost Assistance and Patient Support

As you start treatment with Orenitram, support will be available from the very beginning to help you reach your treatment goals.

United Therapeutics Cares™: United for you

United Therapeutics Cares provides you with ongoing, one-on-one education and support beginning on day one of your United Therapeutics treatment journey. Your dedicated Patient Navigator will personalize support and answer questions about what to expect as you begin treatment, insurance coverage, out-of-pocket cost assistance, and prescription fulfillment.

  • Education & Expectations: keeping you informed about your treatment and what’s next in your United Therapeutics treatment journey
  • Insurance & Coverage: in-house insurance specialists can help explain your plan and navigate coverage options
  • Cost & Savings: working closely with you to learn about financial support options that may be available to you
  • Prescription Coordination: getting you set up with one of our Specialty Pharmacies so that obtaining your prescription and coordinating refills is a simple process
  • Treatment Support: starting on day one of your treatment, count on regular check-ins and personalized education on your condition and United Therapeutics treatment

Work with your provider to enroll in United Therapeutics Cares. Visit UnitedTherapeuticsCares.com to learn more.

If you have any questions, call 1-844-864-8437 to speak with your Patient Navigator, Monday through Friday, 8:30 am - 7 pm ET.

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Cost assistance co-pay program

Zero dollar co-pay icon

With our co-pay program, eligible patients may pay as little as $0 per prescription for Orenitram.

TO ENROLL IN THIS PROGRAM, YOU MUST UNDERSTAND AND AGREE TO COMPLY WITH THE ELIGIBILITY REQUIREMENTS AND TERMS OF USE.

Eligibility requirements for this program are:
Patients must be 18 years or older to use this Program. The Program is valid only for patients with commercial (also known as private) insurance who are taking the medication for an FDA-approved indication. Patients using Medicare, Medicaid, or any other state or federal government program to pay for their medications are not eligible. Patients who start utilizing government coverage during the term of the Program will no longer be eligible. Eligible patients must be residents of the United States or Puerto Rico.

For full program details and Terms and Conditions, visit www.UTcopay.com.

Enroll Now

Join Orenitram Connect

Sign up for Orenitram Connect to receive helpful resources that will give you additional information about Orenitram. These resources include e-newsletters with useful tips, information about your treatment, and other helpful tools.

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Downloadable patient resources

Learn More About Orenitram

Guide to understanding Orenitram

A guide to understanding how adding Orenitram to your treatment plan may help you do more and help control your PAH.

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Talking to your healthcare provider about Orenitram

Use this tool to help you talk to your healthcare provider about whether adding Orenitram to your treatment plan is right for you.

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Starting Treatment With Orenitram

What to expect with Orenitram

Were you just prescribed Orenitram? Here’s what happens next.

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Getting started with the Orenitram Titration Kit

Learn about the Orenitram Titration Kit and how to help set yourself up for success as you begin treatment.

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Support resources as you start treatment with Orenitram

Read more about support resources, including information on dosing, Specialty Pharmacy information, and cost assistance.

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Daily treatment journal and tracker

Use this journal to write down how you are feeling each day, which may help you manage your treatment and keep track of things you want to discuss with your healthcare provider.

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Helpful videos

Titration

Learn how Luisa works with her healthcare team to balance titration and side effects.

Dosing

Watch Jenny discuss how she and her doctor developed a dosing plan that aligns with her treatment goals.

See how the Orenitram Titration Kit works

See how the Orenitram Titration Kit can guide you through the first 3 months of your treatment journey.

Get connected with the Orenitram community

The Orenitram Instagram and Facebook pages provide helpful resources, videos, and support from others, like you.

Understand your Specialty Pharmacy

At United Therapeutics, we work with Specialty Pharmacies that specialize in PAH. The Specialty Pharmacy does more than a typical neighborhood pharmacy and will help with various aspects of your treatment, such as:

  • Scheduling nurse visits to get you started with treatment
  • Offering ongoing assistance through in-person or virtual visits and 24-hour phone support
  • Coordinating the delivery of your medicine
PAH=pulmonary arterial hypertension.

IMPORTANT SAFETY INFORMATION FOR ORENITRAM

Who should not take Orenitram?

Do not take Orenitram if you have severe liver problems.

What should I tell my healthcare provider before taking Orenitram?

Tell your healthcare provider:

  • If you have liver problems or diverticulosis.
  • If you are pregnant, breastfeeding, and/or plan to become pregnant or breastfeed. It is not known if Orenitram will harm your unborn baby or if Orenitram passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with Orenitram.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Orenitram and other medicines may affect each other causing side effects. Do not start any new medicine until you check with your healthcare provider. Especially tell your healthcare provider if you take another medicine that contains treprostinil, such as Remodulin® or Tyvaso®.

How should I take Orenitram?

  • Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider.
  • Orenitram is usually taken 3 times a day (about every 8 hours) or 2 times a day (about every 12 hours). Your healthcare provider will tell you how often you should take Orenitram. If you have side effects, your healthcare provider may tell you to change your dose or when you take Orenitram. Take Orenitram with food.
  • Swallow Orenitram tablets whole. Do not split, chew, crush, or break your Orenitram tablets. Do not take Orenitram tablets that are damaged or broken. If Orenitram tablets are not taken whole, they may release too much medicine at one time. This can lead to side effects.
  • If you miss your dose of Orenitram, take the missed dose as soon as possible with food.
  • If you miss 2 or more doses of Orenitram, call your healthcare provider to see if you need to change your dose.
  • If you take too much Orenitram, call your healthcare provider or go to the nearest hospital emergency room right away.
  • You may see the tablet shell in your stools (bowel movements). This is usually normal. The tablet shell is not digested. If you have diverticulosis, the tablet shell may get stuck in a blind pouch or diverticulum in your intestine.

What are the possible side effects of Orenitram?

Orenitram can cause serious side effects, including worsening of PAH symptoms.

  • Stopping Orenitram suddenly may cause worsening of your PAH symptoms. Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider.
  • The most common side effects of Orenitram include headache, diarrhea, nausea, vomiting, flushing, and pain in arms, legs, and jaw. These are not all of the possible side effects of Orenitram. Tell your healthcare provider if you have any side effect that bothers you or does not go away.
  • Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.

What is Orenitram?

Orenitram is a prescription medicine used to treat pulmonary arterial hypertension (PAH) which is high blood pressure in the arteries of your lungs. Orenitram can help slow down the progression of your disease and improve your ability to exercise. It is not known if Orenitram is safe and effective in children.

The risk information provided here is not comprehensive. To learn more about Orenitram, talk with your healthcare provider.

Please see Full Prescribing Information and Patient Information at www.orenitram.com or call Customer Service at 1-877-UNITHER (1-877-864-8437).

OREISIconOCT19

IMPORTANT SAFETY INFORMATION FOR ORENITRAM

Who should not take Orenitram?

Do not take Orenitram if you have severe liver problems.

What should I tell my healthcare provider before taking Orenitram?

Tell your healthcare provider:

  • If you have liver problems or diverticulosis.
  • If you are pregnant, breastfeeding, and/or plan to become pregnant or breastfeed. It is not known if Orenitram will harm your unborn baby or if Orenitram passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with Orenitram.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Orenitram and other medicines may affect each other causing side effects. Do not start any new medicine until you check with your healthcare provider. Especially tell your healthcare provider if you take another medicine that contains treprostinil, such as Remodulin® or Tyvaso®.

How should I take Orenitram?

  • Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider.
  • Orenitram is usually taken 3 times a day (about every 8 hours) or 2 times a day (about every 12 hours). Your healthcare provider will tell you how often you should take Orenitram. If you have side effects, your healthcare provider may tell you to change your dose or when you take Orenitram. Take Orenitram with food.
  • Swallow Orenitram tablets whole. Do not split, chew, crush, or break your Orenitram tablets. Do not take Orenitram tablets that are damaged or broken. If Orenitram tablets are not taken whole, they may release too much medicine at one time. This can lead to side effects.
  • If you miss your dose of Orenitram, take the missed dose as soon as possible with food.
  • If you miss 2 or more doses of Orenitram, call your healthcare provider to see if you need to change your dose.
  • If you take too much Orenitram, call your healthcare provider or go to the nearest hospital emergency room right away.
  • You may see the tablet shell in your stools (bowel movements). This is usually normal. The tablet shell is not digested. If you have diverticulosis, the tablet shell may get stuck in a blind pouch or diverticulum in your intestine.

What are the possible side effects of Orenitram?

Orenitram can cause serious side effects, including worsening of PAH symptoms.

  • Stopping Orenitram suddenly may cause worsening of your PAH symptoms. Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider.
  • The most common side effects of Orenitram include headache, diarrhea, nausea, vomiting, flushing, and pain in arms, legs, and jaw. These are not all of the possible side effects of Orenitram. Tell your healthcare provider if you have any side effect that bothers you or does not go away.
  • Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.

What is Orenitram?

Orenitram is a prescription medicine used to treat pulmonary arterial hypertension (PAH) which is high blood pressure in the arteries of your lungs. Orenitram can help slow down the progression of your disease and improve your ability to exercise. It is not known if Orenitram is safe and effective in children.

The risk information provided here is not comprehensive. To learn more about Orenitram, talk with your healthcare provider.

Please see Full Prescribing Information and Patient Information at www.orenitram.com or call Customer Service at 1-877-UNITHER (1-877-864-8437).

OREISIconOCT19