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Cost & Support Cost savings & ongoing support

Support from day one

Once you and your healthcare provider decide that Orenitram may help you reach your treatment goals, United Therapeutics, the maker of Orenitram, is here with support at every step in the process.

Orenitram co-pay program

Cost assistance co-pay program

With our co-pay program, eligible patients may pay as little as $0 per prescription for Orenitram.* Learn more at www.UTcopay.com.

*TO ENROLL IN THIS PROGRAM, YOU MUST UNDERSTAND AND AGREE TO COMPLY WITH THE ELIGIBILITY REQUIREMENTS AND TERMS OF USE.

Eligibility requirements for this program are: Patients must be 18 years or older to use this Program. The Program is valid only for patients with commercial (also known as private) insurance who are taking the medication for an FDA-approved indication. Patients using Medicare, Medicaid, or any other state or federal government program to pay for their medications are not eligible. Patients who start utilizing government coverage during the term of the Program will no longer be eligible. Eligible patients must be residents of the United States or Puerto Rico.

For full program details and Terms and Conditions, visit www.UTcopay.com.

United Therapeutics Cares: United for you

United Therapeutics Cares support
United Therapeutics Cares provides you with ongoing, one-on-one education and support beginning on day one of your United Therapeutics treatment journey.

Your dedicated Patient Navigator will personalize support and answer questions about what to expect as you begin treatment, insurance coverage, out-of-pocket cost assistance, and prescription fulfillment.

Education & Expectations

Keeping you informed about your treatment and what’s next in your United Therapeutics treatment journey

Insurance & Coverage

In-house insurance specialists can help explain your plan and navigate coverage options

Cost & Savings

Working closely with you to learn about financial support options that may be available to you

Prescription Coordination

Getting you set up with one of our Specialty Pharmacies so that obtaining your prescription and coordinating refills is a simple process

Treatment Support

Starting on day one of your treatment, count on regular check-ins and personalized education on your condition and United Therapeutics treatment

Work with your provider to enroll in United Therapeutics Cares.
Visit UnitedTherapeuticsCares.com to learn more.

Save this number! If you have any questions, call 1-844-864-8437 to speak with your Patient Navigator, Monday through Friday, 
8:30 am - 7 pm ET.

Learn More
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Personalized information at MyOrenitram.com

When you start Orenitram, visit MyOrenitram.com for an experience thoughtfully created to meet your needs. Inside this patient portal, you'll find support for your specific dosing schedule, tips to help you along the way, and you can listen to stories from patients like you.

Watch to learn about MyOrenitram.com

Get to know your specialty pharmacy

At United Therapeutics, we work with Specialty Pharmacies that specialize in PAH. The Specialty Pharmacy does more than a typical neighborhood pharmacy and will help with various aspects of your treatment, such as:

  • Scheduling nurse visits to get you started with treatment
  • Offering ongoing assistance through in-person or virtual visits and 24-hour phone support
  • Coordinating the delivery of your medicine

United Therapeutics works with 2 Specialty Pharmacies:

Accredo by Evernorth logo

www.accredo.com

Phone: 1-866-344-4874

Fax: 1-800-711-3526

CVS specialty logo

www.cvsspecialty.com

Phone: 1-877-242-2738

Fax: 1-877-943-1000

Join Orenitram Connect

Sign up to learn more about adding Orenitram to your PAH treatment plan. With Orenitram Connect, you'll also receive lifestyle tips, helpful emails, and other useful tools.

Sign Up Now

Get social

The Orenitram Instagram, Facebook, and YouTube pages provide helpful resources, videos, and support from others like you.

Explore educational tools and resources

Tools & Resources

Important Safety 
Information for Orenitram

Who should not take Orenitram?

Do not take Orenitram if you have severe liver problems.

What should I tell my healthcare provider before taking Orenitram?

Tell your healthcare provider:

What is Orenitram?

Orenitram is a prescription medicine used to treat pulmonary arterial hypertension (PAH) which is high blood pressure in the arteries of your lungs. Orenitram can help slow down the progression of your disease and improve your ability to exercise. It is not known if Orenitram is safe and effective in children.

Important Safety Information for Orenitram

Who should not take Orenitram?

Do not take Orenitram if you have severe liver problems.

What should I tell my healthcare provider before taking Orenitram?

Tell your healthcare provider:

  • If you have liver problems or diverticulosis.
  • If you are pregnant, breastfeeding, and/or plan to become pregnant or breastfeed. It is not known if Orenitram will harm your unborn baby or if Orenitram passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with Orenitram.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Orenitram and other medicines may affect each other causing side effects. Do not start any new medicine until you check with your healthcare provider. Especially tell your healthcare provider if you take another medicine that contains treprostinil, such as Remodulin® or Tyvaso®.

What is Orenitram?

Orenitram is a prescription medicine used to treat pulmonary arterial hypertension (PAH) which is high blood pressure in the arteries of your lungs. Orenitram can help slow down the progression of your disease and improve your ability to exercise. It is not known if Orenitram is safe and effective in children.

How should I take Orenitram?

  • Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider.
  • Orenitram is usually taken 3 times a day (about every 8 hours) or 2 times a day (about every 12 hours). Your healthcare provider will tell you how often you should take Orenitram. If you have side effects, your healthcare provider may tell you to change your dose or when you take Orenitram. Take Orenitram with food.
  • Swallow Orenitram tablets whole. Do not split, chew, crush, or break your Orenitram tablets. Do not take Orenitram tablets that are damaged or broken. If Orenitram tablets are not taken whole, they may release too much medicine at one time. This can lead to side effects.
  • If you miss your dose of Orenitram, take the missed dose as soon as possible with food.
  • If you miss 2 or more doses of Orenitram, call your healthcare provider to see if you need to change your dose.
  • If you take too much Orenitram, call your healthcare provider or go to the nearest hospital emergency room right away.
  • You may see the tablet shell in your stools (bowel movements). This is usually normal. The tablet shell is not digested. If you have diverticulosis, the tablet shell may get stuck in a blind pouch or diverticulum in your intestine.

What are the possible side effects of Orenitram?

Orenitram can cause serious side effects, including worsening of PAH symptoms.

  • Stopping Orenitram suddenly may cause worsening of your PAH symptoms. Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider.
  • The most common side effects of Orenitram include headache, diarrhea, nausea, vomiting, flushing, and pain in arms, legs, and jaw. These are not all of the possible side effects of Orenitram. Tell your healthcare provider if you have any side effect that bothers you or does not go away.
  • Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at www.fda.gov/MedWatch or call 1‑800‑FDA‑1088.

What is Orenitram?

Orenitram is a prescription medicine used to treat pulmonary arterial hypertension (PAH) which is high blood pressure in the arteries of your lungs. Orenitram can help slow down the progression of your disease and improve your ability to exercise. It is not known if Orenitram is safe and effective in children.

The risk information provided here is not comprehensive. To learn more about Orenitram, talk with your healthcare provider.

Please see Full Prescribing Information and Patient Information at www.orenitram.com or call Customer Service at 1‑877‑UNITHER (1‑877‑864‑8437).

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