The Orenitram Support Program

The Orenitram Support Program

If you are considering Orenitram, or have already been prescribed Orenitram, the Orenitram Support Program can connect you to information and resources through a series of e-mails and mailings.

* Indicates required fields

First Name * This field is required.

Last Name * This field is required.

E-mail address * This field is required. Please enter a valid e-mail address.

Confirm e-mail address * E-mails must match.

Which of these describes you? *

I am considering Orenitram

I am taking Orenitram

I am a caregiver

Please choose one.

I am at least 18 years old. *

Yes

No

Please choose one.

The following fields are only required if you would like to receive Orenitram Support Program mailings in addition to e-mails.

Address 1 This field is required.

Address 2 (Apartment, suite, unit, building, floor, etc)

City This field is required.

State This field is required.

Select State Alabama Alaska Arizona Arkansas California Colorado Connecticut Delaware District of Columbia Florida Georgia Hawaii Idaho Illinois Indiana Iowa Kansas Kentucky Louisiana Maine Maryland Massachusetts Michigan Minnesota Mississippi Missouri Montana Nebraska Nevada New Hampshire New Jersey New Mexico New York North Carolina North Dakota Ohio Oklahoma Oregon Pennsylvania Rhode Island South Carolina South Dakota Tennessee Texas Utah Vermont Virginia Washington West Virginia Wisconsin Wyoming

Zip Code This field is required. The specified US ZIP code is invalid.

Phone number Why do I need to provide this information? This field is required. Please specify a valid phone number.

Orenitram respects your privacy

By clicking the SUBMIT button, I understand that I am giving United Therapeutics Corporation and its affiliates and business partners permission to use my personal information to provide me with information related to the Orenitram Support Program, as well as treatment options and services provided by United Therapeutics. United Therapeutics may also use my information for internal review of its programs for continuous improvement. I understand that United Therapeutics and its contractors will not sell or rent my personal information. I understand I may revoke my permission at any time by clicking the unsubscribe link at the bottom of the page. For more information, please read the privacy policy by clicking the link below.

Important Safety Information for Orenitram

Do not take Orenitram if you have severe liver problems.

Before you take Orenitram, tell your healthcare provider if you:

• Have liver problems, diverticulosis, or any other medical conditions
• Are pregnant, breastfeeding, and/or plan to become pregnant or breastfeed. It is not known if Orenitram will harm your unborn baby or if Orenitram passes into your breast milk. You and your healthcare provider should decide if you will take Orenitram or breastfeed. You should not do both

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Orenitram and other medicines may affect each other causing side effects. Do not start or stop any new medicine until you check with your healthcare provider. Especially tell your healthcare provider if you take another medicine that contains the same ingredient, treprostinil. Know the medicines you take. Keep a list of them and the dose you take to show to your healthcare provider and pharmacist when you get a new medicine.

Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider. Stopping Orenitram suddenly may cause worsening of your PAH symptoms. If you miss two or more doses of Orenitram, call your healthcare provider. If you take too much Orenitram, call your healthcare provider or go to the nearest hospital emergency room right away.

If Orenitram tablets are not taken whole, they may release too much medicine at one time. This can lead to side effects. Do not split, chew, crush, or break your Orenitram tablets. Do not take Orenitram tablets that are damaged or broken. Take Orenitram with food.

Orenitram can cause serious side effects, including an increased risk of bleeding. This risk could be increased if you are taking blood thinners such as warfarin.

The most common side effects of Orenitram include headache, diarrhea, nausea and flushing. These are not all of the possible side effects of Orenitram. Tell your doctor about any side effects that bother you, get worse over time, or do not go away.

Indication

Orenitram is a prescription medicine used to treat pulmonary arterial hypertension (PAH) which is high blood pressure in the arteries of your lungs. Orenitram may improve your ability to exercise. It is not known if Orenitram is safe and effective in children under 18 years of age.

OREISIdtcJAN16

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.

Please see Full Prescribing Information and Patient Information for Orenitram.

For additional information about Orenitram, call 1-877-UNITHER (1-877-864-8437).

This information is provided for educational purposes only and is not intended as treatment advice. Consult your healthcare provider for treatment advice.

IMPORTANT SAFETY INFORMATION FOR ORENITRAM